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Journal / Biochemistry / 双DNA标尺研究单核苷酸分辨率的核糖体易位机制…
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Biochemistry

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JoVE Journal Biochemistry
双DNA标尺研究单核苷酸分辨率的核糖体易位机制
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双DNA标尺研究单核苷酸分辨率的核糖体易位机制

Article DOI: 10.3791/59918-v • 10:27 min • July 8th, 2019
July 8th, 2019 •
1, 1, 2
1Department of Chemistry, University of Houston, 2Department of Biology and Biochemistry, University of Houston

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开发双DNA标尺测定,以确定核糖体易位过程中的mRNA位置,该位置依赖于形成DNA-mRNA复面的解离力。具有单核苷酸分辨率和达到mRNA两端的能力,可为核糖体易位提供机械见解,并探测其他核酸位移。

Tags

生物化学 问题 149 DNA 标尺 核糖体移位 帧移位 力光谱 磁标记 力诱导残余磁化光谱 mRNA循环 抗生素 原子磁学
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