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Journal / Bioengineering / Gタンパク質共役受容体(GPPC)を組み込んだモデル脂質膜の構築…
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Gタンパク質共役受容体(GPPC)を組み込んだモデル脂質膜の構築
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Gタンパク質共役受容体(GPPC)を組み込んだモデル脂質膜の構築

Article DOI: 10.3791/62830-v • 09:45 min • February 5th, 2022
February 5th, 2022 •
*1, *1, 1
1Mork Family Department of Chemical Engineering and Materials Science, University of Southern California
* These authors contributed equally

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Summary
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このプロトコルは、アガロース膨潤を、巨大な単層脂質小胞(GUV)に組み込むための強力かつ一般化可能な技術として利用し、ここで述べるように、ヒト1Aセロトニン受容体タンパク質(5-HT1AR)の再構成に関して、薬理学的に重要なGタンパク質結合型受容体の1つである。

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バイオエンジニアリング、問題180、
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