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Journal / Bioengineering / Un sistema microfisiologico per studiare…
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Bioengineering

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Un sistema microfisiologico per studiare l'interazione leucocitaria-cellula endoteliale durante l'infiammazione

Article DOI: 10.3791/63312-v • 12:55 min • December 9th, 2021
December 9th, 2021 •
1, 2, 3, 4, 5, 1,2,6
1Department of Mechanical Engineering, Temple University, 2Department of Bioengineering, Temple University, 3Department of Bioengineering, University of Toledo, 4Biomedical Technology, CFD Research Corporation, 5Center for Inflammation and Lung Research, Department of Microbiology, Immunology and Inflammation, Lewis Katz School of Medicine, Temple University, 6Department of Radiation Oncology, Lewis Katz School of Medicine, Temple University

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In questo protocollo, un test microfluido biomimetico, in grado di riprodurre un ambiente microvascolare fisiologicamente rilevante e riprodurre l'intera cascata di adesione/migrazione leucocitaria, viene impiegato per studiare le interazioni leucocitaria-cellula endoteliale nella malattia infiammatoria.

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Bioingegneria Numero 178 sistema microfisiologico interazione leucocita-cellula endoteliale infiammazione adesione migrazione saggio microfluido biomimetico
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