Taipei Medical University-Shuang Ho Hospital 1 article published in JoVE Medicine Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection Chun-Nin Lee1, Li-Hsuan Chiu2,5, Chia-Lang Fang3, Shauh-Der Yeh4, Chun S. Zuo5, Shih-Ching Chen6, Li-Kuo Kuo7, Yun-Ming Wang8, Wen-Fu Thomas Lai2,5,9 1Department of Pulmonary and Critical Care Medicine, Taipei Medical University-Shuang Ho Hospital, 2Department of Research and Department of Dentistry, Taipei Medical University / Shuang-Ho Hospital, 3Department of Pathology, Taipei Medical University, 4Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, 5McLean Imaging Center, McLean Hospital/Harvard Medical School, 6Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, 7Department of Medicine, Mackay Medical College, 8Department of Biological Science and Technology, National Chiao Tung University, 9Graduate Institute of Clinical Medicine, Taipei Medical University To improve serological diagnostic tests for Mycobacterium tuberculosis antigens, we developed superparamagnetic iron oxide nanoprobes to detect extrapulmonary tuberculosis.