Jacobs School of Medicine and Biomedical Science 1 article published in JoVE Behavior Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury Matthew J. McGuire1, Steven M. Gertz1, Jolie D. McCutcheon2, Chelsea R. Richardson3, David J. Poulsen1 1Department of Neurosurgery, Jacobs School of Medicine and Biomedical Science, 2Comparative Medicine Laboratory Animal Facilities, University at Buffalo, 3emka Technologies Here we present a protocol to induce severe TBI with the lateral fluid percussion injury (FPI) model in adult, male Wistar rats. We also demonstrate the use of a wireless telemetry system to collect continuous video-EEG recordings and monitor for epileptiform discharges consistent with post-traumatic epileptogenesis.