CDCF-AOX Lab 1 article published in JoVE Bioengineering A Protocol for Detecting and Scavenging Gas-phase Free Radicals in Mainstream Cigarette Smoke Long-Xi Yu1, Boris G. Dzikovski2, Jack H. Freed2 1CDCF-AOX Lab, 2National Biomedical Center for Advanced ESR Technology (ACERT), Department of Chemistry and Chemical Biology, Cornell University Spin-trapping ESR spectroscopy was used to study the effect of plant antioxidants lycopene, pycnogenol and grape seed extract on scavenging gas-phase free radicals in cigarette smoke.