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Journal / Developmental Biology / Assessment of Maternal Vascular Remodeling During …
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Developmental Biology

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JoVE Journal Developmental Biology
Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
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Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus

Article DOI: 10.3791/53534-v • 06:55 min • December 5th, 2015
December 5th, 2015 •
1,2, 1,2, 1,2
1Department of Obstetrics and Gynaecology, School of Clinical Medicine, University of Cambridge, 2Centre for Trophoblast Research, University of Cambridge

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Resumen
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This protocol describes a technique to assess changes in the maternal vasculature during pregnancy in mice. Using stereological methods, remodeling of the decidual spiral arteries is assessed quantitatively and the results confirmed qualitatively using immunohistochemistry.

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Maternal Vascular Remodeling Pregnancy Mouse Uterus Placenta Blood Supply Arterial Remodeling Process Maternal Immune System Natural Killer Cells Spiral Arteries Hematoxylin And Eosin Staining Vessel Size Analysis Smooth Muscle Actin (SMA) Immunohistochemical Detection Pregnancy Phenotype Pregnancy-related Complications
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