Guangdong Provincial Key Laboratory of Digestive Cancer Research 1 article published in JoVE Medicine Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors Dongjie Yang*1,2, Xun Hou*1, Wentong Lan*3, Minxuan Shen1, Shaohua Yang4, Lele Zhang1, Qinbo Cai1, Yan Qian1, Yuan Lin5, Xia Feng6, Yulong He1,2,4 1Center for Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, 2Guangdong Provincial Key Laboratory of Digestive Cancer Research, 3Department of Endoscopy, The First Affiliated Hospital, Sun Yat-sen University, 4Digestive Medicine Center, The Seventh Affiliated Hospital, Sun Yat-sen University, 5Department of Pathology, The First Affiliated Hospital, Sun Yat-sen University, 6Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University Laparoscopy-endoscopy cooperative surgery is appropriate for the treatment of gastric gastrointestinal stromal tumors less than 5 cm in size. It can achieve the respective advantages of endoscopic and laparoscopic surgeries while avoiding their drawbacks.