סינתזה שלב מוצק של פפטיד Bis פונקציונליות שימוש "בטיחות תפוס" מתודולוגיה

1:55

Loading of First Bis-Peptide, Deprotection of First Bis-Peptide, and Simultaneous Resin Capping

3:43

Coupling Tert-butyl Carbamate (Boc)/tert-butyl Ester(tBu)-protected Functionalized Bis-Amino Acid

5:21

Deprotection of Boc/tBu-protected Functionalized Bis-Amino Acid, Deprotection of Fmoc, and Acylation of the First Bis-Amino Acid

6:55

Removal of the Boc Group from the Resin Bound Amino Acid and Cleavage from the Resin

7:56

Assessment Methods

9:51

Results: Analysis by Liquid Chromatography and Mass Spectroscopy

10:36

Conclusion