The Third Affiliated Hospital of Beijing University of Chinese Medicine 1 article published in JoVE Behavior Analysis of Learning and Memory Ability in an Alzheimer's Disease Mouse Model using the Morris Water Maze Huiling Tian1, Ning Ding2, Mengwei Guo1, Shun Wang1, Zidong Wang1, Hao Liu1, Jiayi Yang1, Yujie Li3, Jingyu Ren1, Jing Jiang4, Zhigang Li1 1School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 2Guang'anmen Hospital of China Academy of Chinese Medical Science, 3The Third Affiliated Hospital of Beijng University of Chinese Medicine, 4School of Nursing, Beijing University of Chinese Medicine Herein, a protocol to conduct the Morris water maze tests to evaluate the ability of learning and memory of Alzheimer’s Disease model mice and to assess the effect of manual acupuncture for treating them is described.