National Cerebral and Cardiovascular Center 1 article published in JoVE Neuroscience A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis Masahiro Tsuji1, Jacques-Olivier Coq2, Yuko Ogawa1, Yumi Yamamoto1, Makiko Ohshima1 1Department of Regenerative Medicine and Tissue Engineering, National Cerebral and Cardiovascular Center, 2Institut de Neurosciences de la Timone, CNRS, Aix Marseille Université Mild intrauterine hypoperfusion was produced by artery stenosis with metal microcoils wrapped around the uterine and ovarian arteries in rats at embryonic day 17. This procedure produced prenatal hypoperfusion and intrauterine growth restriction.
