University of Fukui Faculty of Medical Sciences 1 article published in JoVE Neuroscience Lipid Bilayer Experiments with Contact Bubble Bilayers for Patch-Clampers Masayuki Iwamoto1, Shigetoshi Oiki1 1Department of Molecular Physiology and Biophysics, University of Fukui Faculty of Medical Sciences Here, we present a protocol for the formation of lipid bilayers using a contact bubble bilayer method. A water bubble is blown into an organic solvent, whereby a monolayer is formed at the water-oil interface. Two pipettes are manipulated to dock the bubbles to form a bilayer.
