Juntendo University Shizuoka Hospital 1 article published in JoVE Cancer Research Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer Kiichi Sugimoto1,2, Hirotaka Momose2, Tomoaki Ito1,3, Hajime Orita3, Koichi Sato3, Kazuhiro Sakamoto2, Malcolm V. Brock1 1Department of Surgery, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 2Department of Coloproctological Surgery, Juntendo University Faculty of Medicine, 3Department of Surgery, Juntendo University Shizuoka Hospital Herein, we describe a procedure for genome-wide analysis of DNA methylation in gastrointestinal cancers. The procedure is of relevance to studies that investigate relationships between methylation patterns of genes and factors contributing to carcinogenesis in gastrointestinal cancers.
