ARC Centre of Excellence for Electromaterials Science 1 article published in JoVE Neuroscience A Method for Systematic Electrochemical and Electrophysiological Evaluation of Neural Recording Electrodes Alexander R. Harris1,3, Simeon J. Morgan1,3, Gordon G. Wallace3, Antonio G. Paolini1,3,4 1School of Psychological Science, La Trobe University, 2Intelligent Polymer Research Institute, University of Wollongong, 3ARC Centre of Excellence for Electromaterials Science, 4Health Innovations Research Institute, College of Science, Engineering, and Health, RMIT University Different electrode coatings affect neural recording performance through changes to electrochemical, chemical and mechanical properties. Comparison of electrodes in vitro is relatively simple, however comparison of in vivo response is typically complicated by variations in electrode/neuron distance and between animals. This article provides a robust method to compare neural recording electrodes.
