Research Center Juelich 1 article published in JoVE Biology Terminal H-reflex Measurements in Mice Frederique Wieters*1, Matthias Gruhn*2, Ansgar Büschges2, Gereon R. Fink1,3, Markus Aswendt1 1Faculty of Medicine and University Hospital Cologne, Department of Neurology, University of Cologne, 2Department for Animal Physiology, Institute for Zoology, Biocenter Cologne, University of Cologne, 3Cognitive Neuroscience, Institute of Neuroscience and Medicine (INM-3), Research Center Juelich The clinical evaluation of spasticity based on the Hoffmann reflex (H-reflex) and using electrical stimulation of peripheral nerves is an established method. Here, we provide a protocol for a terminal and direct nerve stimulation for H-reflex quantification in the mouse forepaw.
