Institut de Biologie Structurale 1 article published in JoVE Biochemistry The Automated Crystallography Pipelines at the EMBL HTX Facility in Grenoble Irina Cornaciu1,2, Raphael Bourgeas1, Guillaume Hoffmann1, Florine Dupeux1,3, Anne-Sophie Humm1, Vincent Mariaule1, Andrea Pica1,2, Damien Clavel1,2, Gael Seroul1,2, Peter Murphy1, José Antonio Márquez1,2 1European Molecular Biology Laboratory, 2ALPX S.A.S., 3Institut de Biologie Structurale Here, we describe how to use the automated macromolecular crystallography pipelines for protein-to-structure, rapid ligand-protein complex analysis and large-scale fragment screening based on the CrystalDirect technology at the HTX Laboratory in EMBL Grenoble.
