St. George's University of London 1 article published in JoVE Biology Evaluation of Zebrafish Kidney Function Using a Fluorescent Clearance Assay Sonia Christou-Savina1, Philip L. Beales1, Daniel P. S. Osborn2 1Genetics and Genomic Medicine, Institute of Child Health, University College London, 2 The zebrafish is a popular tool to model chronic kidney disease (CKD). However, their small size makes it impossible to evaluate renal function using traditional methods. We describe a fluorescent dye kidney clearance assay1 that allows quantitative analysis of zebrafish kidney function in CKD.
