UCL Queen Square Institute of Neurology 2 articles published in JoVE Neuroscience Conventional and Threshold-Tracking Transcranial Magnetic Stimulation Tests for Single-handed Operation Hatice Tankisi1, James Howells2, Bülent Cengiz3, Gintaute Samusyte4, Martin Koltzenburg5, Hugh Bostock6 1Department of Clinical Neurophysiology, Aarhus University Hospital, 2Central Clinical School, Faculty of Medicine and Health, University of Sydney, 3Department of Neurology, Gazi University Faculty of Medicine, 4Department of Neurology, Medical Academy, Lithuanian University of Health Sciences, 5Department of Clinical Neurophysiology, National Hospital for Neurology and Neurosurgery; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, 6Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology We present a suite of standardized single- and paired-pulse transcranial magnetic stimulation (TMS) recording protocols, with options for conventional amplitude measurements and threshold-tracking. This program can control three different types of magnetic stimulators and is designed to enable all tests to be performed conveniently by a single operator. Neuroscience Muscle Velocity Recovery Cycles to Examine Muscle Membrane Properties Agnes Witt1, Hugh Bostock2, Werner J. Z'Graggen3, S. Veronica Tan4, Alexander Gramm Kristensen1, Rikke Søgaard Kristensen1, Lotte Hardbo Larsen1, Zennia Zeppelin1, Hatice Tankisi1 1Department of Clinical Neurophysiology, Aarhus University Hospital, 2UCL Queen Square Institute of Neurology, Queen Square House, 3Departments of Neurology and Neurosurgery, Inselspital, Bern University Hospital, University of Bern, 4MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, The National Hospital for Neurology and Neurosurgery Presented here is a protocol for the recording of muscle velocity recovery cycles (MVRCs), a new method of examining muscle membrane properties. MVRCs enable in vivo assessment of muscle membrane potential and alterations in muscle ion channel function in relation to pathology, and it enables the demonstration of muscle depolarization in neurogenic muscles.
