Masaryk Memorial Cancer Institute 1 article published in JoVE Bioengineering Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles Brandon J. Tefft1, Susheil Uthamaraj2, J. Jonathan Harburn3, Martin Klabusay4, Dan Dragomir-Daescu2,5, Gurpreet S. Sandhu1 1Division of Cardiovascular Diseases, Mayo Clinic, 2Division of Engineering, Mayo Clinic, 3School of Medicine, Pharmacy and Health, Durham University, 4Regional Center for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, 5Mayo Clinic College of Medicine, Mayo Clinic Targeted cell delivery is useful in a variety of biomedical applications. The goal of this protocol is to use superparamagnetic iron oxide nanoparticles (SPION) to label cells and thereby enable magnetic cell targeting approaches for a high degree of control over cell delivery and localization.
