Normandie Univ, UNIROUEN, INSERM U1096 1 article published in JoVE Medicine A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit Thomas Clavier1,2, Sébastien Franchina1, Antoine Lefevre-Scelles1, Philippe Gouin1, Emmanuel Besnier1,2, Benoit Veber1 1Department of Anesthesiology and Critical Care, Rouen University Hospital, 2Normandie Univ, UNIROUEN, INSERM U1096 We present a protocol to show the installation of a needle-free connector with positive displacement on a central venous catheter.