MRC-Laboratory of Molecular Biology 1 article published in JoVE Biology High-throughput Measurement of Dictyostelium discoideum Macropinocytosis by Flow Cytometry Thomas Williams1, Robert R. Kay1 1MRC-Laboratory of Molecular Biology, Cambridge, UK Macropinocytosis, large-scale non-specific fluid uptake, is important in many areas of clinical biology including immunology, infection, cancer, and neurodegenerative diseases. Here, existing techniques have been adapted to allow high-throughput, single-cell resolution measurement of macropinocytosis in the macropinocytosis model organism Dictyostelium discoideum using flow cytometry.
