2 articles published in JoVE
Extracellular Recording of Neuronal Activity Combined with Microiontophoretic Application of Neuroactive Substances in Awake Mice Yaneri A. Ayala1, David Pérez-González1, Daniel Duque1,2, Alan R. Palmer3, Manuel S. Malmierca1,4 1Auditory Neuroscience Laboratory, Institute of Neuroscience of Castilla y León, University of Salamanca, 2Neural Systems Laboratory, Institute for Systems Research, University of Maryland, 3Medical Research Council Institute of Hearing Research, 4Department of Cell Biology and Pathology, Faculty of Medicine, University of Salamanca We present methods for the construction of electrodes to simultaneously record extracellular neural activity and release multiple neuroactive substances at the vicinity of the recording sites in awake mice. This technique allows the detailed analysis of putative local synaptic inputs to the neuron of interest.
Making Sense of Listening: The IMAP Test Battery Johanna G. Barry*1, Melanie A. Ferguson*2, David R. Moore*1 1MRC Institute of Hearing Research, 2NIHR, National Biomedical Research Unit in Hearing A test battery (IMAP) for performing an in-depth assessment of auditory and cognitive abilities contributing to listening skills is described. It is quick to administer, child-friendly and free from linguistic confounds. Stimulus generation and protocol management are controlled via a software platform (IHR-STAR) to ensure replicable procedures.