3 articles published in JoVE
The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo Ane M. Holme1,2, Maia B. Holm1,2, Marie C. P. Roland1,3, Hildegunn Horne1,2, Trond M. Michelsen1,3, Guttorm Haugen2,4, Tore Henriksen1,2 1Department of Obstetrics, Oslo University Hospital, 2Institute of Clinical Medicine, University of Oslo, 3Norwegian Advisory Unit on Women's Health, Oslo University Hospital, 4Department of Fetal Medicine, Oslo University Hospital We present a detailed method to study human placental physiology in vivo at term. The method combines blood sampling from the incoming and outgoing vessels on the maternal and fetal sides of the placenta with ultrasound measurements of volume blood flow and placental tissue sampling.
Live Imaging of Drug Responses in the Tumor Microenvironment in Mouse Models of Breast Cancer Elizabeth S. Nakasone1,2, Hanne A. Askautrud2,3, Mikala Egeblad2 1Watson School of Biological Sciences, 2Cold Spring Harbor Laboratory, 3Departments of Medical Genetics, University of Oslo and Oslo University Hospital We describe a method for imaging response to anti-cancer treatment in vivo and at single cell resolution.
Xenotransplantation of Human Stem Cells into the Chicken Embryo Jean-Luc Boulland1, Gabor Halasi1, Nedim Kasumacic1, Joel C. Glover1,2 1Department of Physiology, University of Oslo, 2Norwegian Center for Stem Cell Research, University of Oslo In this paper we present a method for transplanting human stem cells into various regions of the central nervous system of the chicken embryo. This provides an in vivo model for assessing the proliferation and differentiation of various types of human stem cells in embryonic tissue environments.