Cumming School of Medicine 1 article published in JoVE Medicine An Intact Pericardium Ischemic Rodent Model Ali Fatehi Hassanabad1, Darrell D. Belke1, Jeannine Turnbull1, Jameson A. Dundas1, Vishnu Vasanthan1, Guoqi Teng1, Paul W. M. Fedak1, Justin F. Deniset1,2 1Section of Cardiac Surgery, Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, 2Department of Pharmacology and Physiology, University of Calgary This protocol outlines the steps for inducing myocardial infarction in mice while preserving the pericardium and its contents.