Northwestern University Interdepartmental Neuroscience Program 1 article published in JoVE Neuroscience Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing Hongkai Wang1,2, Dom D’Andrea1, Yeon Sik Choi3,4, Yasmine Bouricha1, Grace Wickerson3,4, Hak-Young Ahn3, Hexia Guo3,4, Yonggang Huang3,4,5,6, Milap S. Sandhu7, Sumanas W. Jordan8, John A. Rogers3,4,6,9,10,11,12, Colin K. Franz1,3,13 1Laboratory of Regenerative Rehabilitation, Shirley Ryan AbilityLab, Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, 2Northwestern University Interdepartmental Neuroscience Program, 3Center for Bio-integrated Electronics, Querrey Simpson Institute for Bioelectronics, Northwestern University, 4Department of Materials Science and Engineering, Northwestern University, 5Department of Civil and Environmental Engineering, Northwestern University, 6Department of Mechanical Engineering, Northwestern University, 7Arms and Hands Lab, Shirley Ryan AbilityLab, Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, 8Division of Plastic and Reconstructive Surgery, Biologics, Shirley Ryan AbilityLab, Northwestern University, 9Department of Biomedical Engineering, Northwestern University, 10Department of Neurological Surgery, Northwestern University, 11Department of Chemistry, Northwestern University, 12Department of Electrical and Computer Engineering, Northwestern University, 13The Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine This is a protocol for the surgical implantation and operation of a wirelessly powered interface for peripheral nerves. We demonstrate the utility of this approach with examples from nerve stimulators placed on either the rat sciatic or phrenic nerve.
