Baylor Research Institute 1 article published in JoVE Immunology and Infection Intra-tracheal Administration of Haemophilus influenzae in Mouse Models to Study Airway Inflammation K. Venuprasad1, Balamayooran Theivanthiran1, Brandi Cantarel1 1Baylor Institute for Immunology Research, Baylor Research Institute We demonstrate the procedure for intra-tracheal inoculation of Haemophilus influenzae into the lower respiratory tracts of mice. This is a very useful tool to study signaling pathways that regulate airway inflammation in mouse models.