Sir Mortimer B. Davis Jewish General Hospital 1 article published in JoVE Cancer Research Detection of Lung Tumor Progression in Mice by Ultrasound Imaging Nour Ghaddar1,2, Shuo Wang1, Véronique Michaud1, Urszula Kazimierczak1,3, Nicolas Ah-son1, Antonis E. Koromilas1,4 1Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, 2Division of Experimental Medicine, Faculty of Medicine, McGill University, 3Department of Cancer Immunology, Chair of Medical Biotechnology, Poznan University of Medical Sciences, 4Gerald Bronfman Department of Oncology, Faculty of Medicine, McGill University This protocol describes the steps taken to induce KRAS lung tumors in mice as well as the quantification of formed tumors by ultrasound imaging. Small tumors are visualized in early timepoints as B-lines. At later timepoints, relative tumor volume measurements are achieved by the measurement tool in the ultrasound software.
