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2 articles published in JoVE
A Fully Automated and Highly Versatile System for Testing Multi-cognitive Functions and Recording Neuronal Activities in Rodents Weimin Zheng1, Edgar A. Ycu1 1The Neurosciences Institute, San Diego, CA In this report, we present a fully automated and highly versatile system capable of simultaneously testing multi-cognitive behaviors and recording neuronal activities for rodents.
Neuromodulation and Mitochondrial Transport: Live Imaging in Hippocampal Neurons over Long Durations David B. Edelman*1, Geoffrey C. Owens*1, Sigeng Chen*1 1Department of Experimental Neurobiology, The Neurosciences Institute We describe a protocol that allows imaging of mitochondria in living neurons via fluorescence microscopy over long durations. Imaging over extended periods is accomplished through lentivirus-mediated expression of a mitochondrially targeted fluorescent protein and use of an inexpensive stage-top incubator that was designed and built in our laboratory.