Huntington Medical Research Institutes 1 article published in JoVE Neuroscience WheelCon: A Wheel Control-Based Gaming Platform for Studying Human Sensorimotor Control Quanying Liu1,2,3, Yorie Nakahira2, Zhichao Liang1, Ahkeel Mohideen2, Adam Dai2, Sung Hoon Choi2, Angelina Pan2, Dimitar M. Ho2, John C. Doyle2 1Department of Biomedical Engineering, Southern University of Science and Technology, 2Division of Engineering and Applied Science, California Institute of Technology, 3Neuroscience Center, Huntington Medical Research Institutes WheelCon is a novel, free and open-source platform to design video games that noninvasively simulates mountain biking down a steep, twisting, bumpy trail. It contains components presenting in human sensorimotor control (delay, quantization, noise, disturbance, and multiple feedback loops) and allows researchers to study the layered architecture in sensorimotor control.