2 articles published in JoVE
Single-throughput Complementary High-resolution Analytical Techniques for Characterizing Complex Natural Organic Matter Mixtures Malak M. Tfaily*1,2, Rachel M. Wilson*3, Heather M. Brewer1, Rosalie K. Chu1, Heino M. Heyman4, David W. Hoyt1, Jennifer E. Kyle5, Samuel O. Purvine1 1Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, 2Department of Soil, Water and Environmental Science, University of Arizona, 3Department of Earth Ocean and Atmospheric Sciences, Florida State University, 4Bruker Daltonics Inc., 5Biological Sciences Division, Pacific Northwest National Laboratory This protocol describes a single throughput for complementary analytical and omics techniques culminating in a fully-paired characterization of natural organic matter and microbial proteomics in different ecosystems. This approach permits robust comparisons for identifying metabolic pathways and transformations important for describing greenhouse gas production and predicting responses to environmental change.
Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence Natalia J. Sumi1, Eydis Lima1, John Pizzonia2, Sean P. Orton3, Vinicius Craveiro1, Wonduk Joo1, Jennie C. Holmberg1, Marta Gurrea1, Yang Yang-Hartwich1, Ayesha Alvero1, Gil Mor1 1Department of Obstetrics, Gynecology and Reproductive Sciences, Reproductive Immunology Unit, Yale University School of Medicine, 2NatureMost Laboratories, 3Bruker Preclinical Imaging We describe a non-invasive animal imaging platform that allows the detection, quantification, and monitoring of ovarian cancer growth and recurrence. This intra-peritoneal xenograft model mimics the clinical profile of patients with ovarian cancer.