William Beaumont Hospital View Institution's Website 1 article published in JoVE Biology Monitoring Acupuncture Effects on Human Brain by fMRI Kathleen K. S. Hui1, Vitaly Napadow1, Jing Liu1, Ming Li1, Ovidiu Marina1,2, Erika E. Nixon1, Joshua D. Claunch1, Lauren LaCount1, Tara Sporko1, Kenneth K. Kwong1 1Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 2William Beaumont Hospital FMRI and physiological monitoring is used to study the effects of Acupuncture on the central and peripheral nervous systems. Acupuncture mobilizes a limbic-paralimbic-neocortical network, with great overlap with the default mode network, to modulate neurological activity, possibly related to its autonomic effect in the peripheral nervous system.