New Jersey Institute of Technology

6 articles published in JoVE

• Chemistry

  
  Probing Surface Electrochemical Activity of Nanomaterials using a Hybrid Atomic Force Microscope-Scanning Electrochemical Microscope (AFM-SECM) Xiaonan Shi¹, Qingquan Ma¹, Taha Marhaba¹, Wen Zhang^{1 1}Department of Civil and Environmental Engineering, New Jersey Institute of Technology Atomic force microscopy (AFM) combined with scanning electrochemical microscopy (SECM), namely, AFM-SECM, can be used to simultaneously acquire high-resolution topographical and electrochemical information on material surfaces at nanoscale. Such information is critical to understanding heterogeneous properties (e.g., reactivity, defects, and reaction sites) on local surfaces of nanomaterials, electrodes and biomaterials.

• Medicine

  
  Transplantation of Schwann Cells Inside PVDF-TrFE Conduits to Bridge Transected Rat Spinal Cord Stumps to Promote Axon Regeneration Across the Gap Yee-Shuan Lee¹, Siliang Wu², Treena Livingston Arinzeh³, Mary Bartlett Bunge^{1,4,5 1}The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, ²Department of Materials Science and Engineering, New Jersey Institute of Technology, ³Department of Biomedical Engineering, New Jersey Institute of Technology, ⁴Department of Cell Biology, University of Miami Miller School of Medicine, ⁵Department of Neurological Surgery, University of Miami Miller School of Medicine This article describes a technique to insert a hollow conduit between the spinal cord stumps after complete transection and fill with Schwann cells (SCs) and injectable basement membrane matrix in order to bridge and promote axon regeneration across the gap.

• Bioengineering

  
  A Versatile Method of Patterning Proteins and Cells Anil B. Shrirao*¹, Frank H. Kung*², Derek Yip³, Bonnie L. Firestein², Cheul H, Cho³, Ellen Townes-Anderson^{4 1}Department of Biomedical Engineering, Rutgers University, ²Department of Cell Biology and Neuroscience, Rutgers University, ³Department of Biomedical Engineering, New Jersey Institute of Technology, ⁴Department of Pharmacology, Physiology, and Neuroscience, Rutgers New Jersey Medical School This report describes a simple, easy to perform technique, using low pressure vacuum, to fill microfluidic channels with cells and substrates for biological research.

• Bioengineering

  
  Culturing Mouse Cardiac Valves in the Miniature Tissue Culture System Boudewijn P.T. Kruithof¹, Samuel C. Lieber², Marianna Kruithof-de Julio³, Vincian Gaussin⁴, Marie José Goumans^{1 1}Department of Molecular Cell Biology, Leiden University Medical Center, ²Department of Engineering Technology, New Jersey Institute of Technology, ³Department of Urology, Leiden University Medical Center, ⁴Cardiovascular Research Institute, Department of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School Here, we present an ex vivo flow model in which murine cardiac valves can be cultured allowing the study of the biology of the valve.

• Bioengineering

  
  Axon Stretch Growth: The Mechanotransduction of Neuronal Growth Joseph R. Loverde^1,2, Rosa E. Tolentino^1,2, Bryan J. Pfister^{1 1}Departments of Biomedical Engineering, New Jersey Institute of Technology, ²Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey A unique tissue engineering method was developed to elongate numerous nerve fibers in culture by recapitulating axon stretch growth; a form of nervous system growth whereby nerves elongate in conjunction with growth of the enlarging body.

• Neuroscience

  
  VisualEyes: A Modular Software System for Oculomotor Experimentation Yi Guo¹, Eun H. Kim¹, Tara L. Alvarez^{1 1}Department of Biomedical Engineering, New Jersey Institute of Technology Neural control and cognitive processes can be studied through eye movements. The VisualEyes software allows an operator to program stimuli on two computer screens independently using a simple, custom scripting language. The system can stimulate tandem eye movements (saccades and smooth pursuit) or opposing eye movements (vergence) or any combination.