2 articles published in JoVE
Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery Alejandro Granillo1, Celia A Pena1, Thuy Pham1, Lavannya M Pandit2, George E. Taffet1 1Huffington Center on Aging, Baylor College of Medicine, 2Pulmonary/Critical Care/Sleep Medicine, Michael E. DeBakey Veterans Affairs Medical Center The following protocol describes the methodology for the acquisition and analysis of echocardiographic images used to obtain the Left Atrial Volume (LAV), Aorta (Ao) diameter, and Pulmonary Artery (PA) diameter in mice. This technique is a non-invasive, non-terminal procedure that allows assessment of the cardiopulmonary function.
In vitro Assembly of Semi-artificial Molecular Machine and its Use for Detection of DNA Damage Candace L. Minchew1,2, Vladimir V. Didenko1,2,3 1Neurosurgery, Baylor College of Medicine, 2Michael E. DeBakey Veterans Affairs Medical Center, 3Molecular & Cellular Biology, Baylor College of Medicine We demonstrate the assembly and application of a molecular-scale device powered by a topoisomerase protein. The construct is a bio-molecular sensor which labels two major types of DNA breaks in tissue sections by attaching two different fluorophores to their ends.