Assumption College 1 article published in JoVE Neuroscience Isolation and Culture of Dissociated Sensory Neurons From Chick Embryos Sarah Powell1, Amrit Vinod1, Michele L. Lemons1 1Department of Natural Sciences, Assumption College Cell culture models provide detailed control over environmental conditions and thus provide a powerful platform to elucidate numerous aspects of neuronal cell biology. We describe a rapid, inexpensive, and reliable method to isolate, dissociate, and culture sensory neurons from chick embryos. Details of substrata preparation and immunocytochemistry are also provided.