National Institute of Dental and Craniofacial Research, NIH, DHHS 2 articles published in JoVE Medicine Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans Konstantinia Almpani1,2, Anna Adjei2, Denise K. Liberton1, Payal Verma1, Man Hung*2,3,4, Janice S. Lee*1 1National Institute of Dental and Craniofacial Research, 2College of Dental Medicine, Roseman University of Health Sciences, 3University of Utah School of Medicine, 4George E. Wahlen VA Medical Center Presented here is a detailed protocol for the conduction of three-dimensional cephalometric analysis with the use of human cone beam computed tomography scans. Medicine Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction Renjith Parameswaran Nair1, Changyu Zheng2, Gulshan Sunavala-Dossabhoy1 1Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, 2Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, NIH, DHHS Salivary gland hypofunction, a major adverse effect of head and neck radiotherapy diminishes a patient's quality of life. The demonstration of efficacy of new therapies in animal models is a prerequisite before clinical transition. This protocol describes retroductal administration and local irradiation of rat submandibular glands.
