Supported lipid bilayers and natural membrane particles are convenient systems that can approximate the properties of cell membranes and be incorporated in a variety of analytical strategies. Here we demonstrate a method for preparing microarrays composed of supported lipid bilayer-coated SiO2 beads, phospholipid vesicles or natural membrane particles.
Wittenberg, N. J., Johnson, T. W., Jordan, L. R., Xu, X., Warrington, A. E., Rodriguez, M., Oh, S. Formation of Biomembrane Microarrays with a Squeegee-based Assembly Method. J. Vis. Exp. (87), e51501, doi:10.3791/51501 (2014).