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Neuroscience
Paradigma Stroop dual-task per rilevare deficit cognitivi in pazienti con ictus ad alto funzionam...
Paradigma Stroop dual-task per rilevare deficit cognitivi in pazienti con ictus ad alto funzionam...
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Paradigma Stroop dual-task per rilevare deficit cognitivi in pazienti con ictus ad alto funzionamento

Full Text
3,764 Views
07:42 min
December 16, 2022

DOI: 10.3791/63991-v

Songjun Lin1,2, Qiang Lin3,4,5, Biyi Zhao3,4,6, Yongchun Jiang3,4, Wanqi Zhuang3,4, Delong Chen3,4, Yajie Zhang3,4, Aijia Chen3,4, Qianrong Zhang7, Yuxin Zheng3,4, Jianjun Wang1, Fangqiu Xu8, Xi Qin3,4,9, Yefeng Cai10

1Department of Neurology and Psychology, the Fourth Clinical Medical College,Guangzhou University of Chinese Medicine, Shenzhen Traditional Chinese Medicine Hospital, 2Guangzhou University of Chinese Medicine, 3Department of Rehabilitation Medicine,The Fifth Affiliated Hospital of Guangzhou Medical University, 4Department of Rehabilitation Medicine,Guangzhou Medical University, 5Key Laboratory of Biological Targeting Diagnosis, Therapy and Rehabilitation of Guangdong Higher Education Institutes,The Fifth Affiliated Hospital of Guangzhou Medical University, 6School of Traditional Chinese Medicine,Jinan University, 7Health College of Guangdong Pharmaceutical University, 8Department of Clinical Medicine,Guangzhou Medical University, 9Department of Rehabilitation Medicine,Panzhihua Central Hospital, 10Department of Neurology and Psychology,the Second Affiliated Hospital of Guangzhou University of Chinese Medicine

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Overview

This study introduces a dual-task Stroop paradigm aimed at detecting cognitive dysfunction in high-functioning stroke patients, a group often overlooked by traditional assessment scales. The research evaluates the performance of stroke patients using fNIRS, aiming to enhance clinical assessment and cognitive training methods.

Key Study Components

Area of Science

  • Neuroscience
  • Cognitive Assessment
  • Stroke Rehabilitation

Background

  • Conventional clinical assessment scales often fail to detect cognitive deficits in high-functioning stroke patients.
  • Identifying cognitive dysfunction accurately is crucial for effective rehabilitation.
  • Elevating assessment methods can pave the way for tailored cognitive training.

Purpose of Study

  • To establish a novel assessment protocol utilizing the dual-task Stroop paradigm.
  • To identify cognitive deficits that conventional skills miss in high-functioning stroke patients.
  • To enhance treatment strategies based on cognitive performance metrics.

Methods Used

  • Utilized fNIRS for real-time brain activity monitoring during cognitive tasks.
  • Implemented a series of cognitive assessments including MoCA, CDR, and Stroop tasks.
  • Conducted tests while participants performed specified cognitive tasks, integrating a balance component to evaluate dual-task performance.
  • Assured participant safety with strict observational guidelines during testing.

Main Results

  • Stroke patients exhibited longer reaction times and lower accuracy during dual-task evaluations compared to healthy subjects.
  • Notable differences in brain function metrics were observed, specifically lower beta values in stroke patients.
  • Results underscore the effectiveness of the dual-task approach in revealing cognitive deficits.

Conclusions

  • This study establishes a framework for more sensitive cognitive assessment in high-functioning stroke patients.
  • The dual-task Stroop paradigm may lead to more individualized treatment strategies.
  • Ultimately, these findings contribute to understanding cognitive mechanisms in stroke recovery.

Frequently Asked Questions

What advantages does the dual-task Stroop paradigm offer?
It allows for the identification of subtle cognitive deficits in stroke patients not detectable by standard assessments, enhancing rehabilitation strategies.
How are cognitive deficits assessed in this study?
Cognitive assessments include MoCA, CDR, and dual-task Stroop tests, measuring attention, memory, and executive function.
What is the role of fNIRS in this protocol?
fNIRS is used to monitor brain activity in real-time while patients perform the Stroop tasks, facilitating a link between cognitive performance and neural correlates.
What safety measures are taken during the assessment?
Participants are observed closely to prevent injuries, particularly when performing dual tasks that involve physical balance.
Can the protocol be adapted for other patient populations?
Yes, the dual-task Stroop paradigm could be modified for use with other neurological conditions where cognitive deficits need identification.
What future research directions does this study suggest?
Future studies should explore different types and difficulty levels of dual tasks to further refine cognitive assessments.

Le scale di valutazione clinica non sono abbastanza sensibili alla disfunzione cognitiva nei pazienti con ictus ad alto funzionamento. Il paradigma dual-task presenta vantaggi e potenzialità nella valutazione e nell'allenamento cognitivo della disfunzione cognitiva. Lo studio qui propone un paradigma Stroop a doppio compito per identificare la disfunzione cognitiva nei pazienti con ictus ad alto funzionamento.

Il nostro protocollo di studio potrebbe essere utilizzato per identificare il deficit cognitivo in pazienti con ictus ad alto funzionamento che non sono facilmente rilevabili dalle capacità di valutazione convenzionali. Questo protocollo di studio è quello di fornire nuove idee per capire l'effetto nel fallimento della valutazione clinica generale per i pazienti con ictus ad alto funzionamento. Questo protocollo di studio potrebbe essere facilmente utilizzato nella pratica clinica.

Ad esempio, il medico potrebbe modificare la strategia di trattamento in base al tempo di reazione di Stroop e alla velocità corretta. A dimostrare la procedura sarà Siqi Huang, terapista della riabilitazione; Siqing Wang, terapista occupazionale; Yajie Zhanga, fisioterapista, Biyi Zhao, terapista occupazionale del nostro laboratorio. Reclutare pazienti colpiti da ictus con condizioni stabili allo stadio 4 di Brunnstrom, come confermato dall'esame di imaging.

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