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Health Status: The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures.

Blood Withdrawal I

JoVE 10246

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN


Blood collection is a common requirement for research studies that involve mice and rats. The method of blood withdrawal in mice and rats is dependent upon the volume of blood needed, the frequency of the sampling, the health status of the …

 Lab Animal Research

Anatomy of the Intestines

JoVE 10830

Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occur in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.

The small intestine is an ~22 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the small intestine is highly convoluted and covered in finger-like extensions called villi, each containing hundreds of microvilli. The folds, villi, and microvilli of the small intestine amplify the surface area of absorption 60 to 120 times. The increased surface area provides ample opportunity for nutrients to be absorbed. The small intestine connects to the stomach by the pyloric sphincter, which closes off when chyme moves into the duodenum—the beginning of the small intestine. The middle and largest part of the small intestine is the jejunum. The ileum ends the small intestine, where it attaches to the large intestine by the ileocecal valve. The large intestine starts at the cecum. The appendix, a small lymphatic structure, dangles from the bottom of the cecum. Above the cecum, starts the ascending colon followed by the transverse colon. They absorb most of the remaining

 Core: Biology

Anesthesia Induction and Maintenance

JoVE 10263

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN


The Guide for the Care and Use of Laboratory Animals ("The Guide") states that pain assessment and alleviation are integral components of the veterinary care of laboratory animals.1 The definition of anesthesia is the loss …

 Lab Animal Research

Reproductive Techniques for Ovarian Monitoring and Control in Amphibians

1Reproductive Sciences, San Diego Zoo Institute for Conservation Research, 2Recovery Ecology, San Diego Zoo Institute for Conservation Research, 3Menagerie du Jardin des Plantes, Museum National d'Histoire Naturelle, 4Cincinnati Zoo & Botanical Garden, Center for Conservation and Research of Endangered Wildlife

JoVE 58675

 Biology

Whole-cell Patch-clamp Recordings of Isolated Primary Epithelial Cells from the Epididymis

1School of Life Science and Technology, ShanghaiTech University, 2Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 3University of Chinese Academy of Sciences, 4Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University

JoVE 55700

 Developmental Biology

Structured Motor Rehabilitation After Selective Nerve Transfers

1Clinical Laboratory for Bionic Extremity Reconstruction, Medical University of Vienna, 2Bioengineering Department, Imperial College London, 3Master's Degree Program Health Assisting Engineering, University of Applied Sciences FH Campus Wien, 4Department of Orthopedics and Trauma Surgery, Medical University of Vienna, 5Division of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna

JoVE 59840

 Medicine

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers

1Centre for Human Psychopharmacology, Swinburne University of Technology, 2Department of Anaesthesia and Pain Management, St. Vincent's Hospital Melbourne, 3Brain and Psychological Science Research Centre, Swinburne University of Technology, 4Department of Anaesthesiology, University of Auckland

JoVE 56881

 Neuroscience

Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precision-cut Lung Slices

1Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), German Center for Lung Research (DZL), Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of REBIRTH Cluster of Excellence, 2Institute for Pathology, Hannover Medical School, German Center for Lung Research (DZL), Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), 3Division of Thoracic and Vascular Surgery, Klinikum Region Hannover (KRH), 4Department of Cardiothoracic, Transplantation and Vascular Surgery (HTTG), Hannover Medical School, German Center for Lung Research (DZL), Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), 5Institute of Pharmacology and Toxicology, RWTH Aachen University, 6Institute for Immunology, Hannover Medical School

JoVE 57042

 Immunology and Infection

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model

1Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, 2Departamento de Medicina y Cirugía Animal, Facultad de Veterinaria, Universidad de Murcia, 3Institute of Virology and Immunology (IVI), 4Departamento de Anatomía y Anatomía Comparada, Facultad de Veterinaria, Universidad de Murcia, 5Unidad de Trasplante Hematopoyético y Terapia Celular, Departamento de Hematología, Hospital Universitario Virgen de la Arrixaca, IMIB, Universidad de Murcia

JoVE 56699

 Medicine

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

1Department of Electrical and Computer Engineering, Lehigh University, 2Department of Mechanical Engineering, Lehigh University, 3Department of Biomedical Engineering, Southern University of Science and Technology, 4Department of Technology R&D, Nexcelom Bioscience LLC, 5Department of Bioengineering, Lehigh University, 6Center for Photonics and Nanoelectronics, Lehigh University

JoVE 59020

 Cancer Research

Imaging Cell Interaction in Tracheal Mucosa During Influenza Virus Infection Using Two-photon Intravital Microscopy

1Faculty of Biomedical Sciences, Institute for Research in Biomedicine, Università della Svizzera italiana (USI), 2Graduate School of Cellular and Molecular Sciences, Faculty of Medicine, University of Bern, 3Institute of Computational Science, Università della Svizzera italiana (USI)

JoVE 58355

 Immunology and Infection

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

1Program for the Study and Control of Tropical Diseases -PECET-School of Medicine, University of Antioquia, 2School of Agrarian Sciences, University of Antioquia

JoVE 3533

 Immunology and Infection

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

1Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 2Early Psychosis: Interventions and Clinical-detection (EPIC) lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 3National Institute for Health Research, Maudsley Biomedical Research Centre, South London and Maudsley National Health Service (NHS) Foundation Trust, 4Institute of Health Informatics, University College London, 5Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 6Health Data Research UK London, University College London, 7OASIS service, South London and Maudsley National Health Service (NHS) Foundation Trust, 8Department of Brain and Behavioral Sciences, University of Pavia

Video Coming Soon

JoVE 60794

 JoVE In-Press

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

1School of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, 2Institute of Rehabilitation Medicine, Shanghai Academy of Traditional Chinese Medicine, 3Department of Sports Medicine, Shanghai University of Sport, 4Department of Respiratory Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine

JoVE 59765

 Behavior

The Lower Body Positive Pressure Treadmill for Knee Osteoarthritis Rehabilitation

1Department of Rehabilitation, The Fifth Affiliated Hospital of Guangzhou Medical University, 2Experiment Education Model Center of Rehabilitation Medicine, Guangzhou Medical University, 3Department of Physical Medicine and Rehabilitation, Geisinger Health System, 4Department of Rehabilitation Medicine, New York University School of Medicine

JoVE 59829

 Medicine

Data Collection on Marine Litter Ingestion in Sea Turtles and Thresholds for Good Environmental Status

1Italian National Institute for Environmental Protection and Research (ISPRA), 2Institute for Coastal Marine Environment-National Research Council (IAMC-CNR), 3EPHE, PSL Research University, UMR 5175 CE3FE, CNRS, UM, Univ P. Valery, SupAgro, IRD, INRA, Biogéographie et Écologie des Vertébrés, 4Cavanilles Institute of Biodiversity and Evolutionary Biology, University of Valencia, 5Departamento de Oceanografia e Pescas, Instituto do Mar/Okeanos, Universidade dos Açores, 6MARE - Marine and Environmental Sciences Centre, Universidade dos Açores, 7Muséum national d' Histoire naturelle (MNHN), 8Sea Turtle Research and Application Center (DEKAMER), Pamukkale University, 9Institute of Oceanografy Hellenic Centre for Marine Research (HCMR), 10Institut National des Sciences et Technologies de la Mer (INSTM), 11University of Las Palmas de Gran Canaria, 12INDICIT consortium

JoVE 59466

 Environment

Induction of Mouse Lung Injury by Endotracheal Injection of Bleomycin

1Servizio di Allevamento e Sperimentazione Animale, Polo ScientificoTecnologico, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS)-Istituto Nazionale Ricovero e Cura Anziani (INRCA), 2Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, 3UOS Centro di Terapia Cellulare "G. Lanzani", Azienda Socio Sanitaria Territoriale (ASST) Papa Giovanni XXIII

JoVE 58922

 Immunology and Infection

Effectiveness of the Air Stripping in Two Salmonid Fish, Rainbow Trout (Oncorhynchus Mykiss) and Brown Trout (Salmo Trutta Morpha fario)

1Department of Gamete and Embryo Biology, Institute of Animal Reproduction and Food Research, Polish Academy of Science, 2Department of Salmonid Fish Research, The Stanisław Sakowicz Inland Fisheries Institute

JoVE 56894

 Developmental Biology

Rat Model of Adhesive Capsulitis of the Shoulder

1Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center and Harvard Medical School, 2Carl J. Shapiro Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, 3Departments of Biomedical Engineering, Chemistry, and Medicine, Boston University, 4Department of Orthopaedic Surgery, Yerevan State Medical University

JoVE 58335

 Bioengineering

Transdermal Measurement of Glomerular Filtration Rate in Mice

1Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, 2Department of Cellular and Molecular Physiology, University of Liverpool, 3MediBeacon GmbH, 4Department of Veterinary Pathology and Public Health, Institute of Veterinary Science, University of Liverpool

JoVE 58520

 Medicine
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