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Povidone-Iodine: An iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The iodine may be radiolabeled for research purposes.

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment

1Graduate Institute of Medical Sciences, National Defense Medical Center, 2Department and Graduate Institute of Biology and Anatomy, National Defense Medical Center, 3Department of Gerontological Health Care, National Taipei University of Nursing and Health Sciences, 4Division of Rheumatology/Immunology/Allergy, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, 5Department of Plastic and Reconstructive Surgery, Tri-Service General Hospital, 6Department of Nursing, Yuanpei University, 7Department of Physiology and Biophysics; Graduate Institute of Physiology, National Defense Medical Center, 8Division of Urology, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center

Video Coming Soon

JoVE 57942


 JoVE In-Press

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury

1Department of Anesthesiology and Intensive Care Medicine, University Medical Center, 2Department of Anesthesia and Critical Care, University of Würzburg, 3Department of General, Visceral, Vascular and Paediatric Surgery, Department of Surgery I, University of Würzburg, 4Department of Internal Medicine I, Division of Nephrology, University Hospital Würzburg, 5Department of Physiology and Pharmacology, West Virginia University School of Medicine

Video Coming Soon

JoVE 54448


 JoVE In-Press

A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats

1Behavioral Neuroscience, Experimental and Biological Psychology, Philipps-Universität Marburg, 2Behavioral Neurosciences Institute (INeC), 3Thomas RECORDING GmbH, 4Department of Neurophysics, Philipps-Universität Marburg

JoVE 56299


 Behavior

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes

1Department of Medicine, University of Hong Kong-Shenzhen Hospital, 2The Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, 3School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, 4Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences, Joint School of Life Sciences, Guangzhou Medical University, 5Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 6Laboratory of RNA, Chromatin, and Human Disease, CAS Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 7Research Centre of Heart, Brain, Hormone, and Healthy Ageing, Li Ka Shing Faculty of Medicine, University of Hong Kong, 8Hong Kong-Guangdong Stem Cell and Regenerative Medicine Research Centre, University of Hong Kong and Guangzhou Institutes of Biomedicine and Health

Video Coming Soon

JoVE 57556


 JoVE In-Press

Long Term Intravital Multiphoton Microscopy Imaging of Immune Cells in Healthy and Diseased Liver Using CXCR6.Gfp Reporter Mice

1Department of Medicine III, RWTH University-Hospital Aachen, 2IZKF Aachen Core Facility "Two-Photon Imaging", RWTH University-Hospital Aachen, 3Institute for Laboratory Animal Science & Experimental Surgery, RWTH Aachen University, 4Institute for Pharmacology, RWTH University-Hospital Aachen

JoVE 52607


 Immunology and Infection

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

1Department of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, 2Department of Nursing, Georgetown University, School of Nursing and Health Studies, 3Department of Human Science, Georgetown University, School of Nursing and Health Studies, 4School of Medicine, Georgetown University Medical Center, 5Department of Pathology and Neuropathology, Medical University of Gdańsk, 6Department of Oncology, Georgetown University Medical Center, 7Department of Pathology, Georgetown University Medical Center

JoVE 54532


 Cancer Research

Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs

1Department of Ophthalmology, Seoul National University Bundang Hospital, 2Department of Ophthalmology, College of Medicine, Seoul National University, 3Department of Ophthalmology, Hanyang University Hospital, 4Department of Ophthalmology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, 5Department of Clinical Pharmacology, Seoul National University Hospital, 6Department of Clinical Pharmacology, Seoul National University Bundang Hospital

JoVE 53878


 Medicine

Experimental Glaucoma Induced by Ocular Injection of Magnetic Microspheres

1Ocular Biology and Therapeutics, University College London Institute of Ophthalmology, 2University College London Institue of Ophthalmology, 3Moorfields Eye Hospital, 4NIHR Biomedical Research Centre, Moorfields Eye Hospital, 5Schepens Eye Research Institute, Harvard Medical School, 6Hoffman-La Roche

JoVE 52400


 Medicine

A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies

1Department of Bioengineering, Department of Orthopedics, University of Colorado Anschutz Medical Campus, 2Department of Orthopedics, University of Colorado Anschutz Medical Campus, 3Department of Chemical & Biological Engineering, Colorado School of Mines, 4Department of Orthopedics, Gates Center for Regenerative Medicine, University of Colorado Anschutz Medical Campus

JoVE 55571


 Medicine

Rat Model of Widespread Cerebral Cortical Demyelination Induced by an Intracerebral Injection of Pro-Inflammatory Cytokines

1Research Unit of Experimental Neurotraumatology, Institute of Neurosurgery, Medical University Graz, 2Department of Neurology, Medical University Graz, 3Centre for Molecular Medicine, Department of Clinical Neuroscience, Karolinska Institutet, 4Centre for Molecular Medicine, Department of Medical Biochemistry and Biophysics, Karolinska Institutet

Video Coming Soon

JoVE 57879


 JoVE In-Press

The Rabbit Blood-shunt Model for the Study of Acute and Late Sequelae of Subarachnoid Hemorrhage: Technical Aspects

1Department of Intensive Care Medicine, University and Bern University Hospital (Inselspital), 2Department of Neurosurgery, Kantonsspital Aarau, 3Laboratories for Neuroscience Research in Neurosurgery, Boston Children's Hospital, 4Harvard Medical School, Boston Children's Hospital, 5Department of Neurosurgery, University and Bern University Hospital (Inselspital), 6Department of Neurosurgery, University Hospital Cologne, 7Institute of Pathology, Länggasse Bern

JoVE 52132


 Medicine

Murine Spinotrapezius Model to Assess the Impact of Arteriolar Ligation on Microvascular Function and Remodeling

1Department of Biomedical Engineering, University of Virginia, 2Department of Biomedical Engineering, California Polytechnic State University, 3Office of Animal Welfare, University of Virginia, 4Department of Biomedical Engineering & Institute for Computational Medicine, Johns Hopkins University

JoVE 50218


 Medicine

A Technique for Subcutaneous Abdominal Adipose Tissue Biopsy via a Non-diathermy Method

1FAME Laboratory, Department of Exercise Science, University of Thessaly, 2Institute of Sport, Faculty of Education, Health and Wellbeing, University of Wolverhampton, 3Faculty of Medicine, School of Health Sciences, University of Thessaly, 4School of Physical Education and Exercise Science, University of Thessaly

JoVE 55593


 Medicine

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

1Department of Urology, University of Minnesota, 2Masonic Cancer Center, University of Minnesota, 3Microbiology, Immunology, and Cancer Biology Graduate Program, University of Minnesota, 4Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, 5Simmons Cancer Institute

JoVE 55080


 Cancer Research

An Anesthesia, Surgery, and Harvest Method for the Evaluation of Transpedicular Screws Using an In Vivo Porcine Lumbar Spine Model

1Department of Orthopaedic Surgery, Chonbuk National University School of Medicine, Chonbuk National University Hospital, 2Department of Orthopaedic Surgery, University of Seonam College of Medicine, Presbyterian Medical Center, 3Wowanimal Hospital, 4Department of Emergency Medicine, Inje University Busan Paik Hospital

JoVE 55225


 Medicine

A Rat Model of Orthotopic Liver Transplantation Using a Novel Magnetic Anastomosis Technique for Suprahepatic Vena Cava Reconstruction

1Shaanxi Provincial Center for Regenerative Medicine and Surgical Engineering, First Affiliated Hospital, Xi'an Jiaotong University, 2Institute of Advanced Surgical Technology and Engineering, First Affiliated Hospital, Xi'an Jiaotong University, 3Department of Hepatobiliary Surgery, First Affiliated Hospital, Xi'an Jiaotong University, 4Organ Transplantation Center, Tianjin First Center Hospital

JoVE 56933


 Medicine

Vein Interposition Model: A Suitable Model to Study Bypass Graft Patency

1Transplant and Stem Cell Immunobiology Lab, University Heart Center Hamburg, 2Department of Surgery, Transplant and Stem Cell Immunobiology Lab, University of California San Francisco (UCSF), 3Cardiovascular Research Center (CVRC) and DZHK German Center for Cardiovascular Research), partner site Hamburg/Kiel/Luebeck, 4Cardiovascular Surgery, University Heart Center Hamburg

JoVE 54839


 Medicine

Manipulation of Epileptiform Electrocorticograms (ECoGs) and Sleep in Rats and Mice by Acupuncture

1Department of Sports, Health & Leisure, College of Tourism, Leisure and Sports, Aletheia University, Tainan Campus, 2Department of Neurology, Mackay Memorial Hospital and Mackay Medical College, 3Department of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, 4Graduate Institute of Brain & Mind Sciences, College of Medicine, National Taiwan University, 5Graduate Institute of Acupuncture Science, College of Chinese Medicine, China Medical University

JoVE 54896


 Behavior

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