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Die Anwendung des dauerhaften mittleren Hirnarterie Ligation in der Maus
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Die Anwendung des dauerhaften mittleren Hirnarterie Ligation in der Maus

Article DOI: 10.3791/3039-v • 08:28 min • July 25th, 2011
July 25th, 2011 •
1, 2, 3
1Department of Pharmacology and Physiology, University of Rochester, 2Department of Neurology, University of Alabama at Birmingham, 3Departments of Anesthesiology, Pharmacology and Physiology, University of Rochester

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A. cerebri media (MCA) Ligation ist eine Technik, fokaler zerebraler Ischämie im Tiermodell zu studieren. Bei dieser Methode ist die mittlere Hirnarterie durch Kraniotomie freigelegt und ligiert durch Kauterisation. Diese Methode liefert gut reproduzierbare Infarktvolumen und erhöhte postoperative Überlebensrate im Vergleich zu anderen Methoden zur Verfügung.

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Medizin Gehirn Schlaganfall Maus mittleren Hirnarterie Ligation
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