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En screenbar<em> In vivo</em> Assay for mitokondrie modulatorer Brug Transgene Bioluminescent<em> Caenorhabditis elegans</em
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A Screenable In Vivo Assay for Mitochondrial Modulators Using Transgenic Bioluminescent Caenorhabditis elegans
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11:43 min

October 16, 2015

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Chapters

  • 00:05Title
  • 02:33Nematode Culture (Days 1-6)
  • 05:33Nematode Treatment (Day 7)
  • 07:44Nematode Fluorescence and Bioluminescence Quantification (Day 8)
  • 09:01Results: Representative C. elegans Bioluminescence after Drug Treatment
  • 10:50Conclusion

Summary

자동 번역

A protocol is described for in vivo detection of effects of mitochondrial inhibitors in the model organism Caenorhabditis elegans and for identification of potential enhancing compounds. This protocol can be used to screen drug libraries for compounds modulating mitochondrial function.

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