Waiting
로그인 처리 중...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Biochemistry / Metodo per identificare piccole molecole…
JoVE Journal
Biochemistry

JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.

JoVE Journal Biochemistry
Metodo per identificare piccole molecole inibitori della interazione proteina-proteina tra HCN1 e TRIP8b
MS2-Affinity Purification Coupled with RNA Sequencing in Gram-Positive Bacteria
Journal (Biochemistry)
MS2-Affinity Purification Coupled with RNA Sequencing in Gram-Positive Bacteria
Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR
Journal (Biochemistry)
Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR
 
Click here for the English version

Metodo per identificare piccole molecole inibitori della interazione proteina-proteina tra HCN1 e TRIP8b

Article DOI: 10.3791/54540-v • 10:20 min • November 11th, 2016
November 11th, 2016 •
*1, *1, 2, 3, 1, 1, 4, 1,5
1Davee Department of Neurology and Clinical Neurosciences, Feinberg School of Medicine, Northwestern University, 2Center for Molecular Innovation and Drug Discovery, Northwestern University, 3Department of Pharmacology, Feinberg School of Medicine, Northwestern University, 4High Throughput Analysis Laboratory, Department of Molecular Biosciences, Northwestern University, 5Department of Physiology, Feinberg School of Medicine, Northwestern University
* These authors contributed equally

챕터

요약
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

L'interazione tra i canali HCN e la loro subunità accessoria è stato identificato come un obiettivo terapeutico nel Disturbo Depressivo Maggiore. Qui, un metodo di polarizzazione basato fluorescenza per identificare piccole molecole inibitrici di questa interazione proteina-proteina, è presentato.

Tags

Biochimica lo screening ad alto rendimento scoperta di nuovi farmaci le interazioni proteina-proteina fluorescenza polarizzata HCN TRIP8b
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter