Waiting
로그인 처리 중...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Cancer Research / 患者衍生的胰腺癌异质异种移植模型,使用斑马鱼幼虫作为比较药物评估的宿主…
JoVE Journal
Cancer Research

JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.

JoVE Journal Cancer Research
患者衍生的胰腺癌异质异种移植模型,使用斑马鱼幼虫作为比较药物评估的宿主
Induction and Diagnosis of Tumors in Drosophila Imaginal Disc Epithelia
Journal (Cancer Research)
Induction and Diagnosis of Tumors in Drosophila Imaginal Disc Epithelia
A 3D Spheroid Model as a More Physiological System for Cancer-Associated Fibroblasts Differentiation and Invasion In Vitro Studies
Journal (Cancer Research)
A 3D Spheroid Model as a More Physiological System for Cancer-Associated Fibroblasts Differentiation and Invasion In Vitro Studies
 
Click here for the English version

患者衍生的胰腺癌异质异种移植模型,使用斑马鱼幼虫作为比较药物评估的宿主

Article DOI: 10.3791/59507-v • 09:56 min • April 30th, 2019
April 30th, 2019 •
*1, *2,3, *1, 2,3, 1, 1, 2,3, 2,4,5,6, 1
1Department of Biochemistry and Molecular Biology, Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, School of Basic Medical Sciences, Fudan University, 2National Human Genetic Resources Sharing Service Platform (2005DKA21300), 3Fudan University Shanghai Cancer Center, 4Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, 5Department of Oncology, Shanghai Medical College, Fudan University, 6Pancreatic Cancer Institute, Fudan University
* These authors contributed equally

챕터

요약
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

该协议描述了基于病毒的双荧光标记肿瘤异种移植模型中的优化过程,使用幼虫斑马鱼作为宿主。这种异质异种异种移植模型模仿胰腺癌在体内微环境的组织组成,并作为在个性化zPDX(斑马鱼患者衍生异种移植)模型中评估药物反应的更精确的工具。

Tags

癌症研究 问题 146 癌症研究 肿瘤异种移植 斑马鱼 胰腺癌 体内药物评估 BCL2L1
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter