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Journal / Neuroscience / Hybrid Micro drive system med genvindes…
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Neuroscience

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JoVE Journal Neuroscience
Hybrid Micro drive system med genvindes opto-Silicon Probe og tetrode for dual-site high density optagelse i frit bevægende mus
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Hybrid Micro drive system med genvindes opto-Silicon Probe og tetrode for dual-site high density optagelse i frit bevægende mus

Article DOI: 10.3791/60028-v • 08:57 min • August 10th, 2019
August 10th, 2019 •
1, 1,2, 1
1Department of Psychiatry, University of Texas Southwestern Medical Center, 2Department of Neuroscience, University of Texas Southwestern Medical Center

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Denne protokol beskriver opførelsen af en hybrid Micro drive array, der tillader implantation af ni uafhængigt justerbare tetrodes og en justerbar opto-silicium sonde i to hjerneområder i frit bevægende mus. Også påvist er en metode til sikkert at inddrive og genbruge opto-silicium sonde til flere formål.

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Neurovidenskab in vivo Elektrofysiologi kronisk optagelse hybrid Micro drive array tetrode genindvindings-opto-silicium sonde optogenetik Multisite optagelse frit bevægelige mus enkelt enhed lokale felt potentiale dorsale hippocampus CARBID dorsale mediale entorhinal cortex
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