Right ventricle (RV) dysfunction is critical to the pathogenesis of cardiovascular disease, yet limited methodologies are available for its evaluation. Recent advances in ultrasound imaging provide a noninvasive and accurate option for longitudinal RV study. Herein, we detail a step-by-step echocardiographic method using a murine model of RV pressure overload.
Cheng, H., Fisch, S., Cheng, S., Bauer, M., Ngoy, S., Qiu, Y., Guan, J., Mishra, S., Mbah, C., Liao, R. Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography. J. Vis. Exp. (84), e51041, doi:10.3791/51041 (2014).