The Third Affiliated Hospital of Beijing University of Chinese Medicine 2 articles published in JoVE Medicine Application of Acupotomy in a Knee Osteoarthritis Model in Rabbit Xing LongFei1, Guo Yan2, Chen XiLin1, Hu TingYao1, Zhu WenTing3, Ma WeiWei1, Du Mei1, Xu Yue1, Guo ChangQing1 1School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 2Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine affiliated with Capital Medical University, 3The Third Affiliated Hospital of Beijing University of Chinese Medicine In this protocol, a knee osteoarthritis model was prepared using the modified Videman method, and the operation procedures and precautions of acupotomy are detailed. The effectiveness of acupotomy has been demonstrated by testing the mechanical properties of quadriceps femoris and tendon and the mechanical and morphological properties of cartilage. Behavior Analysis of Learning and Memory Ability in an Alzheimer's Disease Mouse Model using the Morris Water Maze Huiling Tian1, Ning Ding2, Mengwei Guo1, Shun Wang1, Zidong Wang1, Hao Liu1, Jiayi Yang1, Yujie Li3, Jingyu Ren1, Jing Jiang4, Zhigang Li1 1School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, 2Guang'anmen Hospital of China Academy of Chinese Medical Science, 3The Third Affiliated Hospital of Beijng University of Chinese Medicine, 4School of Nursing, Beijing University of Chinese Medicine Herein, a protocol to conduct the Morris water maze tests to evaluate the ability of learning and memory of Alzheimer’s Disease model mice and to assess the effect of manual acupuncture for treating them is described.