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JoVE Journal Bioengineering
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Generering af heterogene stof gradienter på tværs af Cancer populationer på en Microfluidic Evolution Accelerator for real-time observation

Article DOI: 10.3791/60185-v • 10:24 min • September 19th, 2019
September 19th, 2019 •
1, 2, 1, 2, 1, 1
1Princeton University, 2Johns Hopkins Medical Institute

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Vi præsenterer en mikrofluidisk Cancer-on-chip model, "Evolution Accelerator" teknologi, som giver en kontrollerbar platform for langsigtede real-time kvantitative undersøgelser af Cancer dynamik inden for veldefinerede miljømæssige forhold på enkelt-celle Niveau. Denne teknologi forventes at fungere som en in vitro-model for grundforskning eller præklinisk lægemiddeludvikling.

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Bioengineering mikrofabrikation kræft-on-a-chip tumor mikromiljø kemoterapi gradient resistens celle migration
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