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JoVE Journal Neuroscience
In vivo Positronemissionstomografi for at afsløre aktivitetsmønstre induceret af dyb hjernestimulering hos rotter
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In vivo Positronemissionstomografi for at afsløre aktivitetsmønstre induceret af dyb hjernestimulering hos rotter

Article DOI: 10.3791/63478-v • 09:36 min • March 23rd, 2022
March 23rd, 2022 •
1, 2,3, 2,3, 1,2,3,4, 2,4,5
1Centro Nacional de Investigaciones Cardiovasculares (CNIC), 2Laboratorio de Imagen Médica, Instituto de Investigación Sanitaria Gregorio Marañón, 3Departamento de Bioingeniería e Ingeniería Aeroespacial, Universidad Carlos III de Madrid, 4CIBER de Salud Mental (CIBERSAM), 5High Performance Research Group in Physiopathology and Pharmacology of the Digestive System (NeuGut), Universidad Rey Juan Carlos

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Vi beskriver en præklinisk eksperimentel metode til at evaluere metabolisk neuromodulation induceret af akut dyb hjernestimulering med in vivo FDG-PET. Dette manuskript omfatter alle eksperimentelle trin, fra stereotaxisk kirurgi til anvendelse af stimuleringsbehandling og erhvervelse, behandling og analyse af PET-billeder.

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Neurovidenskab udgave 181 stereotaxisk kirurgi dyb hjernestimulering positronemissionstomografi [18F] -fluorodeoxyglucose neurostimulering dyremodeller
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