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Chapter 11

Meiosis

What is Meiosis?
Meiosis is the process by which diploid cells divide to produce haploid daughter cells. In humans, each diploid cell contains 46 chromosomes, half…
Meiosis I
Meiosis is a carefully orchestrated set of cell divisions, the goal of which—in humans—is to produce haploid sperm or eggs, each…
Meiosis II
Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23…
Crossing Over
Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I,…
Nondisjunction
During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or…
Chromatin Spread Preparations for the Analysis of Mouse Oocyte Progression from Prophase to Metaphase II
Chromatin spread techniques have been widely used to assess the dynamic localization of various proteins during gametogenesis, particularly for…
Using Fluorescence <em>In Situ</em> Hybridization (FISH) to Monitor the State of Arm Cohesion in Prometaphase and Metaphase I <em>Drosophila</em> Oocytes
In humans, chromosome segregation errors in oocytes are responsible for the majority of miscarriages and birth defects. Moreover, as women age, their…
Spatial and Temporal Analysis of Active ERK in the <em>C. elegans</em> Germline
The evolutionarily conserved extracellular signal transducing RTK-RAS-ERK pathway is an important kinase-signaling cascade that controls…

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