Summary
American Biologist Martin Chalfie shared the 2008 Nobel Prize in Chemistry with Roger Tsien and Osamu Shimomura for their discovery and development of the Green Fluorescent Protein (GFP). Chalfie subcloned the coding sequence of GFP and expressed it in both E. coli and C. elegans, demonstrating for the first time that no other factor was required for GFP luminescence.
References
- Chalfie, M. GFP: Lighting up life. PNAS. 106 (25), 10073-10080 (2009).
- Chalfie, M. Autobiography [Internet]. , The Nobel Foundation. Available from: http://nobelprize.org/nobel_prizes/chemistry/laureates/2008/chalfie-autobio.html (c2003).
- Chalfie, M. Green fluorescent protein as a marker for gene expression. Science. 263 (5148), 802-805 (1994).